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Heroin can be injected, inhaled by snorting or sniffing, or smoked. All three routes of administration deliver the drug to the brain very rapidly, which contributes to its health risks and to its high risk for addiction, which is a chronic relapsing disease caused by changes in the brain and characterized by uncontrollable drug-seeking no matter the consequences.

Heroin /ˈhɛroʊɪn/ (diacetylmorphine or morphine diacetate, also known as diamorphine (BAN, INN[3])) and commonly known by its street names of H, smack, boy, horse, brown, black, tar, and others is an opioid analgesic originally synthesized by C.R. Alder Wright in 1874 by adding two acetyl groups to the molecule morphine, which is found naturally in the opium poppy. It is the 3,6-diacetyl ester of morphine. Administered intravenously by injection, heroin is two to four times more potent than morphine and is faster in its onset of action.

Illicit heroin is sometimes available in freebase form, dulling the sheen and consistency to a matte-white powder.Because of its lower boiling point, the freebase form of heroin is also smokable. It is prevalent in heroin coming from Afghanistan, which in 2004 produced roughly 87% of the world supply in illicit raw opium.However, the production rate in Mexico has risen sixfold from 2007 to 2011, changing that percentage and placing Mexico as the second largest opium producer in the world.It is a legally prescribed and controlled drug in the United Kingdom. It is supplied in tablets or injections for the same symptoms as morphine is. In Netherlands, Switzerland, Denmark, U.K., Germany and some other countries, heroin is also available for long term use in the form of opioid replacement therapy

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